Structural and Signaling Roles of the Cytoskeleton in Health & Disease
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CA1 Hippocampus Maintenance, Function and Integrity
Abnormalities in the hippocampus are associated with neuropsychiatric diseases characterized by cognitive dysfunction...
The Cytoskeleton in Epilepsy:
Cause, Consequence or Bystander?
Epilepsy is a chronic condition whose hallmark feature is the occurrence of spontaneous recurrent seizures, and is typically associated with comorbid conditions, including learning and memory deficits, anxiety and depression...
Pathogenic Mechanisms in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is the most common form of human motor neuron disease...
From Mitotic Spindle to DNA Damage Response
The microtubule-associated protein TPX2 is well known for its roles in promoting spindle assembly and regulating mitosis...
Genetic Predisposition Factors in Alzheimer Disease
There is currently no treatment for Alzheimer disease (AD), the most common form of senile dementia affecting ~47 million people worldwide...
p600 Links Microtubules to the Endoplasmic Reticulum
Protein 600 is a humongous 600 kDa polypeptide...
